Hrusovksy’s pitch to me is roughly the same as the one he just gave Jeff Miller, the NFL’s senior vice president for health and safety—skittering from drones, to driverless cars, to Tesla, to heart attacks and diabetes. “I’m still addicted to pastries at night,” Hrusovsky says before circling back to his thesis: Quanterix’s machines are on the brink of delivering a revolution in medicine, as scientists use them to detect diseases earlier, target them more precisely, and create breakthrough treatments for cancer, heart disease, diabetes, and Alzheimer’s, to name a few. ... Discovering, for instance, that half its linemen show signs of CTE could starve the league of talent or force changes that make it unrecognizable to fans. And football isn’t alone: CTE presents similarly dire questions for hockey, soccer, and ultimate fighting, among other contact sports. ... The method is a thousand times more sensitive than the Elisa, capable of detecting molecules in concentrations as low as 30,000 per drop—the equivalent, Hrusovsky says, of finding a grain of sand in 2,000 swimming pools.
The company’s mission: to build a Bell Labs of aging research. It hoped to extend the human life span by coming up with a breakthrough as important, and as useful to humanity, as the transistor has been. ... Google’s founders created an academic-biotech hybrid they call an R&D company to follow up on such clues, providing nearly unlimited funding to a group of top researchers. ... despite the hype around its launch—Time magazine asked, “Can Google Solve Death?”—Calico has remained a riddle, a super-secretive company that three years in hasn’t published anything of note, rebuffs journalists, and asks visiting scientists to sign nondisclosure agreements. ... Right now, there’s no proven test for a person’s “biological” age; finding one would be scientifically useful and possibly lucrative. ... For all these diseases, aging is the single biggest risk factor. An 80-year-old is 40 times as likely to die from cancer as someone middle-aged. The risk for Alzheimer’s rises by 600 times. But what if it were possible to postpone all these deaths by treating aging itself? … The experiment will generate millions of readings—for levels of growth hormones and glucose, among other things. Churchill wouldn’t say how much Calico is paying, but simply feeding that many mice could cost $3 million.