Human genomics is just the beginning: the Earth has 50 billion tons of DNA. What happens when we have the entire biocode? ... By 2020, many hospitals will have genomic medicine departments, designing medical therapies based on your personal genetic constitution. Gene sequencers – machines that can take a blood sample and reel off your entire genetic blueprint – will shrink below the size of USB drives. Supermarkets will have shelves of home DNA tests, perhaps nestled between the cosmetics and medicines, for everything from whether your baby will be good at sports to the breed of cat you just adopted, to whether your kitchen counter harbours enough ‘good bacteria’. We will all know someone who has had their genome probed for medical reasons, perhaps even ourselves. Personal DNA stories – including the quality of the bugs in your gut– will be the stuff of cocktail party chitchat. ... Due to satellite imaging, we can see the entire surface of our planet. There can be no undiscovered land masses. The map of the world is complete. And we should expect the same thing for genetics. DNA testing will become so pervasive it will transform the medical, legal and social foundations of society. If blanket genome sequencing takes off, it will be impossible to obscure human relationships or ignore the content of our DNA. ... One of the greatest achievements of the coming century will be the characterisation of the Biocode, not just as a list of genomes of different species, but as patterns of interacting communities. ... By 2050 we should aim to finally have a handle not only on human genetic diversity but on the biodiversity of the planet.