December 20, 2016
When I returned to addiction, it was as a scientist studying the addicted brain. The data were indisputable: brains change with addiction. I wanted to understand how – and why. I wanted to understand addiction with fastidious objectivity, but I didn’t want to lose touch with its subjectivity – how it feels, how hard it is – in the process. ... One explanation is that addiction is a brain disease. The United States National Institute on Drug Abuse, the American Society of Addiction Medicine, and the American Medical Association ubiquitously define addiction as a ‘chronic disease of brain reward, motivation, memory and related circuitry’ ... If only the disease model worked. Yet, more and more, we find that it doesn’t. First of all, brain change alone isn’t evidence for brain disease. Brains are designed to change. ... we now know that drugs don’t cause addiction. ... One idea is that addicts voluntarily choose to remain addicted: if they don’t quit, it’s because they don’t want to. ... The view that addiction arises through learning, in the context of environmental forces, appears to be gathering momentum.
Translate made its debut in 2006 and since then has become one of Google’s most reliable and popular assets; it serves more than 500 million monthly users in need of 140 billion words per day in a different language. It exists not only as its own stand-alone app but also as an integrated feature within Gmail, Chrome and many other Google offerings, where we take it as a push-button given — a frictionless, natural part of our digital commerce. ... Google’s decision to reorganize itself around A.I. was the first major manifestation of what has become an industrywide machine-learning delirium. Over the past four years, six companies in particular — Google, Facebook, Apple, Amazon, Microsoft and the Chinese firm Baidu — have touched off an arms race for A.I. talent, particularly within universities. ... What is at stake is not just one more piecemeal innovation but control over what very well could represent an entirely new computational platform: pervasive, ambient artificial intelligence. ... When he has an opportunity to make careful distinctions, Pichai differentiates between the current applications of A.I. and the ultimate goal of “artificial general intelligence.” Artificial general intelligence will not involve dutiful adherence to explicit instructions, but instead will demonstrate a facility with the implicit, the interpretive. It will be a general tool, designed for general purposes in a general context.
Williams’ discovery of the mysterious block was followed by dozens of reports of similar findings on beaches across western Europe. The blocks, materializing from the Atlantic surf, would cast the spotlight on gutta percha, a Victorian commodity whose obscurity belied its crucial place in modern communications. The humble latex would accelerate global telecommunications to a previously unimagined pace; cement the British empire’s grip over the world’s critical messaging systems; and spur industry and academia to devise some of the foundational theories of modern physics. ... The Victorian system of submarine cables literally laid the foundation, in many cases, for today’s fiber-optic networks. The globe-spanning networks of the day spawned business titans, and technological innovators, that bear close parallels to today’s internet-enabled tycoons. Gutta percha was largely replaced by polyethylene by the 1950s, ending a century of industrial telecommunications use. ... in 1832, a Scottish surgeon stationed in Singapore with the East India Company named William Montgomerie wrote a paper about gutta percha’s unique properties: it could be moulded in hot water but it hardened as it cooled. ... It was as if the Elon Musks or Steve Jobs of the day were all focused on the same, potentially world-altering technology. ... Pender’s businesses left a legacy. Vestiges of his cable empire live on in today’s telecom conglomerates. His firms formed the core of Cable & Wireless
The overuse of antibiotics has transformed what had been a hypothetical menace into a clear and present one: superbugs, bacteria that are highly resistant to antibiotics. By British government estimates, about 700,000 people die each year from antibiotic-resistant infections worldwide. If trends continue, that number is expected to soar to 10 million a year globally by 2050—more people than currently die from cancer. ... Research has found that as much as 90 percent of the antibiotics administered to pigs pass undegraded through their urine and feces. This has a direct impact on farmed seafood. The waste from the pigpens at the Jiangmen farm flowing into the ponds, for example, exposes the fish to almost the same doses of medicine the livestock get—and that’s in addition to the antibiotics added to the water to prevent and treat aquatic disease outbreaks. The fish pond drains into a canal connected to the West River, which eventually empties into the Pearl River estuary, on which sit Guangzhou, Shenzhen, Hong Kong, and Macau. The estuary receives 193 metric tons (213 tons) of antibiotics a year, Chinese scientists estimated in 2013. ... distribution networks that move the seafood around the world are often as murky as the waters in which the fish are raised. Federal agencies trying to protect public health face multiple adversaries: microbes rapidly evolving to defeat antibiotics and shadowy seafood companies that quickly adapt to health regulations to circumvent them, moving dirty seafood around the world in much the same way criminal organizations launder dirty money. ... China’s rates of drug resistance remain among the highest in the world. ... harvested in China but was passed through Malaysia, where it acquired Malaysian certificates of origin. This illegal transshipping, as the maneuver is called
Ask any Iraq War veteran about Jersey, Alaska, Texas, and Colorado and you will be surprised to get stories not about states, but about concrete barriers. Many soldiers deployed to Iraq became experts in concrete during their combat tours. Concrete is as symbolic to their deployments as the weapons they carried. No other weapon or technology has done more to contribute to achieving strategic goals of providing security, protecting populations, establishing stability, and eliminating terrorist threats. This was most evident in the complex urban terrain of Baghdad, Iraq. Increasing urbanization and its consequent influence on global patterns of conflict mean that the US military is almost certain to be fighting in cities again in our future wars. Military planners would be derelict in their duty if they allowed the hard-won lessons about concrete learned on Baghdad’s streets to be forgotten.
Bringing people back from death’s door is Catena’s moonlight gig – she is on shift from 6pm to 2am six to eight times a month. By day, she is the managing director of Catena Zapata, the flagship brand of a family-owned company that sells bottles worth over $140m a year, making it Argentina’s second-biggest wine exporter. The firm was founded in 1902 by her great-grandfather Nicola Catena, and she assumed the reins from her father Nicolás in 2009. She spends four months a year in Argentina overseeing the winery’s operations, and two more as the olive-skinned, pony-tailed “face of Argentine wine”, promoting her products at tastings and dinners across the globe. She manages her staff of 120 via Skype and WhatsApp. ... Catena insists she sees her role as that of a detective, not an inventor. And she has modelled the CIW not after the development arm of a pharmaceutical firm, synthesising precious new compounds from scratch, but rather the upstream division of an oil company, searching for natural treasures the Earth has hidden away. ... how can destroying wine help Catena Zapata make its tipples taste better rather than worse? The answer is that the CIW is using baking as a kind of stress test: all wines subjected to this treatment will suffer, but some will suffer more and others less.